DEVELOPMENT OF HIGH CELL DENSITY CULTIVATION STRATEGIES FOR IMPROVED MEDIUM CHAIN LENGTH POLYHYDROXYALKANOATE PRODUCTIVITY USING PSEUDOMONAS PUTIDA LS46

Development of High Cell Density Cultivation Strategies for Improved Medium Chain Length Polyhydroxyalkanoate Productivity Using Pseudomonas putida LS46

High cell density (HCD) fed-batch cultures are widely perceived as a requisite for high-productivity polyhydroxyalkanoate (PHA) cultivation processes.In this work, a reactive pulse feed strategy (based on real-time CO2 or dissolved oxygen (DO) measurements as feedback variables) was used to control an oxygen-limited fed-batch process for improved p

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PD-1 immunotherapy in pancreatic cancer: current status

Abstract.Pancreatic ductal adenocarcinoma is the known kind of tumor biologically featured as high malignant degree, lack of effective methods for diagnosis and treatment, which reflects its unpleasant prognosis.Recently, with the breakthrough of burgeoning therapeutic methods, the flush of dawn for pancreatic cancer nearly arrives.Nowadays, beside

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Clinical and Genetic Aspects of Chronic Pyelonephritis in Children: the Structure of Addiction and Primary Prognosis

Currently studying the mechanisms of recognition of foreign agents, which is implemented by Toll-like receptor of innate immune system, has become arrethe bush balm one of the main tasks of clinical immunology.The aim of our study was an analysis of the association between Toll-like receptor 4 gene polymorphism (Asp299Gly) and main pathogens of uri

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Investigating the epidemiological relevance of secretory otitis media and neighboring organ diseases through an Internet search

Background This study examined the epidemiological correlations between secretory otitis media (SOM) and diseases of neighboring organs.We measured changes in disease incidences during the 2020 COVID-19 pandemic using Internet big data spanning from 2011 to 2021.Methods This study used the Baidu Index (BI) to determine the search volume for the ter

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